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DEVELOPMENT, SECURITY, AND COOPERATION
Biomedical Lab Training Course for Scientists from Central/Eastern Europe and the Newly Independent States
Schedule for the first week of the course (3-10 June)
Sunday, 3 June 2001
All day Check-in at the Hotel of the Institute of Biochemistry and Biophysics (IBB), ul. Pawinskiego, 5f. Information packets including badges, city maps, and textbooks (for those who did not receive them by mail) will be left at the reception desk. Since everyone is arriving on different schedules, all day today is free for individual sightseeing or rest.
18:00 Kelly Robbins will be at the IBB Hotel to distribute per diem and travel reimbursement payments (she will also be available after dinner for those who cannot be there before)
19:00 Dinner in the IBB cafeteria
Monday, 4 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:30 General Introduction to Course (Dr. R. Andrew Byrd) - IBB Room 7 (Hall A, ground floor)
10:30 - 12:30 Lab Session I
12:30 - 13:30 Lunch in the IBB Cafeteria
13:30 - 14:30 Lecture: Multidimensional Spectroscopy (Dr. R. Andrew Byrd) - IBB Room 7
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture (Topic and Speaker to be Determined) - IBB room E (Hall B, 1st floor)
18:00 - 20:00 Welcome Reception and Dinner - IBB Cafeteria
20:00 - 21:00 Tutorial and Discussion Session - IBB Room 7
Tuesday, 5 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Data Analysis (Dr. Kevin Gardner) - IBB Room 7
10:00 - 12:30 Lab Session I
12:30 - 13:30 Lunch in the IBB Cafeteria
13:30 - 14:30 Lecture: Isotopic Labeling (Dr. Kevin Gardner) - IBB Room 7
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture (Topic and Speaker to be Determined) - IBB Room E
18:00 - 20:00 Dinner in the IBB Cafeteria
20:00 - 21:00 Tutorial and Discussion Session - IBB Room 7
Wednesday, 6 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Dipolar Coupling I (Dr. Eike Brunner) - IBB Room 7
10:00 - 12:30 Lab Session I
12:30 - 13:30 Lunch in the IBB Cafeteria
13:30 - 14:30 Lecture: Structural Calculation I (Dr. Michael Nilges) - IBB Room 7
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture (Topic and Speaker to be Determined) - IBB Room E
18:00 - 20:00 Dinner in the IBB Cafeteria
20:00 - 21:00 Tutorial and Discussion Session - IBB Room 7
Thursday, 7 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Structural Calculation II (Dr. Michael Nilges) - IBB Room 7
10:00 - 12:30 Lab Session I
12:30 - 13:30 Lunch in the IBB Cafeteria
13:30 - 14:30 Lecture: Dipolar Coupling II (Dr. Eike Brunner) - IBB Room 7
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture (Topic and Speaker to be Determined) - IBB Room E
18:00 - 20:00 Dinner in the IBB Cafeteria
20:00 - 21:00 Tutorial and Discussion Session - IBB Room 7
Friday, 8 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Structure Analysis (Dr. Walter Chazin) - IBB Room 7
10:00 - 12:30 Lab Session I
12:30 - 13:30 Lunch in the IBB Cafeteria
13:30 - 14:30 Lecture: Dynamics (Dr. Andrzej Ejchart) - IBB Room 7
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture (Topic and Speaker to be Determined) - IBB Room E
18:00 - 20:00 Dinner in the IBB Cafeteria
20:00 - 21:00 Tutorial and Discussion Session - IBB Room 7
Saturday, 9 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Lecture: Coupling Structure and Dynamics to Biology - IBB Room 7
10:00 - 12:00 Group Presentations, Roundtable Discussion, Evaluation - IBB Room 7
12:00 - 13:00 Lunch in the IBB Cafeteria
13:00 - 16:00 Free time for packing, rest, individual sightseeing in local area
16:00 Departure from IBB to Warsaw Old Town for sightseeing and dinner
Sunday, 10 June 2001
8:00 - 9:00 Breakfast served at hotel
10:00 Departure for Poznan by bus (5-hour trip - we will stop on the way for lunch)
16:00 Arrival in Poznan, accommodation at the conference center of the Institute of Bioorganic Chemistry (IBCH)
19:00 Dinner in the IBCH cafeteria
Schedule for the second week of the course (11-17 June)
Monday, 11 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 11:30 Lab Session I
11:30 - 12:30 Lecture: Introduction to Protein Crystallography (Dr. Lennart Sjolin)
12:30 - 13:30 Lunch in the IBCH Cafeteria
13:30 - 14:30 Lecture: Crystallization of Proteins (Dr. Alexander McPherson)
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture: Structure of a Novel Serine-Carboxyl Proteinase (Dr. Alexander Wlodawer)
18:15 - 20:00 Dinner and Rest
20:00 - 21:00 Tutorial and Discussion Session
Tuesday, 12 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 11:30 Lab Session I
11:30 - 12:30 Lecture: Theory of Diffraction (Dr. Mariusz Jaskólski)
12:30 - 13:30 Lunch in the IBCH Cafeteria
13:30 - 14:30 Lecture: Crystallographic Data Collection (Dr. Zbigniew Dauter)
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture: Can the Structure of a Bacterial Enzyme Explain Proteasome Activation? (Dr. Matthias Bochtler)
18:15 - 20:00 Dinner and Rest
20:00 - 21:00 Tutorial and Discussion Session
Wednesday, 13 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 11:30 Lab Session I
11:30 - 12:30 Lecture: Structure Solution (MIR/SIR) (Dr. Lennart Sjolin)
12:30 - 13:30 Lunch in the IBCH Cafeteria
13:30 - 14:30 Lecture: Structure Solution (MAD) (Dr. Matthias Bochtler)
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture: Anomalous Scattering and High Resolution Structures (Dr. Zbigniew Dauter)
18:15 - 20:00 Dinner and Rest
20:00 - 21:00 Tutorial and Discussion Session
Thursday, 14 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 11:30 Lab Session I
11:30 - 12:30 Lecture: Structure Solution (MR) (Dr. Matthias Bochtler)
12:30 - 13:30 Lunch in the IBCH Cafeteria
13:30 - 14:30 Lecture: Model Building (Dr. Grzegorz Bujacz)
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture: Electron Transfer Mechanism (Dr. Lennart Sjolin)
18:15 - 20:00 Dinner and Rest
20:00 - 21:00 Tutorial and Discussion Session
Friday, 15 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 11:30 Lab Session I
11:30 - 12:30 Lecture: Refinement, Part I (Dr. Alexander Wlodawer)
12:30 - 13:30 Lunch in the IBCH Cafeteria
13:30 - 14:30 Lecture: Refinement, Part II (Dr. Lennart Sjolin)
14:30 - 17:00 Lab Session II
17:15 - 18:00 Public Lecture: Applications of Atomic Force Microscopy to Macromolecular Crystallography (Dr. Alexander McPherson)
18:15 - 20:00 Dinner and Rest
20:00 - 21:00 Tutorial and Discussion Session
Saturday, 16 June 2001
8:00 - 9:00 Breakfast is served at the hotel
9:00 - 10:00 Validation/Comparison with NMR (Dr. Zbigniew Dauter)
10:00 - 11:00 Final Quality Checks and Deposition (Dr. Mariusz Jaskólski)
11:00 - 12:00 Summary of the Course (Dr. Alexander Wlodawer)
12:00 - 13:00 Lunch in the IBCH Cafeteria
13:00 Departure for excursion to local castle and other sites, followed by dinner in a country restaurant
Sunday, 17 June 2001
8:00 - 9:00 Breakfast is served at the hotel (for those who do not have to depart earlier in the morning)
Departure of instructors and students for home!
Schedule of Laboratory Practicals for IBB/Warsaw
All lab sessions will be held in the IBB NMR Labs (Rooms 35-38, Hall B, Floor -1)
There will be 5 groups of 5 - A, B, C, D, and E
Day
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NMR I
AM
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NMR
II
PM
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Data Proc.
AM
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Data Assn/Anal.
PM
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StrCalc. I
AM
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StrCalc. II
PM
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StrAnal. I
AM
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StrAnal. II
PM
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Dipolar Coupling
AM
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Dynamics
PM
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|
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Byrd
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Byrd
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Gardner
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Gardner
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Nilges
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Nilges
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Chazin
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Chazin
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Brunner
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Ejchart
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MON
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A
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A
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B+E
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B
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|
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C+D
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C+D
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E
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TUE
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C
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C
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D
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D+E
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A+B
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A+B
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|
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E
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WED
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B
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B
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|
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C+D
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C+D
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E
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E
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A
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A
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THU
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D
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D
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C
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C
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E
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E
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A
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A
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B
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B
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FRI
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E
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E
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A
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A
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|
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B
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B
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C+D
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C+D
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Schedule of Laboratory Practicals for IBCH/Poznan
Students will be divided into 5 groups (5 students per group).
Each day Monday-Friday, the schedule will be the same, with groups rotating.
1) AM Data collection Zbigniew Dauter
PM Structure solution Zbigniew Dauter & Matthias Bochtler
2) AM Crystallization A. McPherson & Grzegorz Bujacz
PM Crystallization A. McPherson & Grzegorz Bujacz
3) AM Structure solution (SIR/MIR) Mariusz Jaskolski & Alexander Wlodawer
PM Structure solution (MR) Mariusz Jaskolski
4) AM Structure refinement Lennart Sjolin
PM Structure refinement Lennart Sjolin
5) AM Graphics and model building Matthias Bochtler
PM Validation and deposition Alexander Wlodawer 
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